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Can Extra Virgin Olive Oil Work Like Ibuprofen? Here’s What the Science Says

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Extra virgin olive oil (EVOO) has long been praised for its heart-health benefits—but could it also act as a natural alternative to over-the-counter pain relief? Surprisingly, research suggests that it might. Two naturally occurring compounds in high-quality EVOO—oleocanthal and oleoresin—have been found to reduce inflammation in ways similar to ibuprofen.

These compounds target the same inflammation-producing enzymes that ibuprofen blocks. That familiar peppery sensation you get in the back of your throat when tasting fresh olive oil? That’s a sign of oleocanthal doing its work. Researchers say this “bite” mimics how ibuprofen feels and functions in the body, at least on a biochemical level.

However, while the lab results are promising, research in humans is still limited. The pain-relieving compounds are present only in small amounts, and mostly in high-quality, cold-pressed EVOO that has been properly stored and handled. So while EVOO may help reduce low-grade, chronic inflammation over time, it’s not meant to replace your go-to painkillers or any medication prescribed by your doctor.

That said, incorporating two to four tablespoons of extra virgin olive oil into your daily meals may offer gentle, long-term support for joint comfort and overall well-being. Beyond potential pain relief, EVOO supports heart health, helps lower bad cholesterol, improves blood circulation, and may even help regulate blood pressure.

EVOO isn’t a direct substitute for ibuprofen, but it is a smart, natural way to support your body’s inflammation response. And when it comes to long-term health, adding a little high-quality olive oil to your routine goes a long way when it comes to long-term health.

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